Intravenous infusions of sulfated insulin normalize plasma glucose levels in pancreatectomized canines. Blood glucose regulation using an open-loop insulin supply system in pancreatectomized canines given glucose infusions. Optimal glycaemic control in unrestrained diabetic canine using programmed compound squarewave insulin infusions. Increased urea synthesis in insulin-dependent diabetic canine maintained normoglycemic: impact of portal insulin administration and meals protein content material. I. Portal sq. waves. Comparison between closed-loop portal and peripheral venous insulin delivery systems for an synthetic endocrine pancreas. In the diabetics blood glucose was regulated first by closed-loop after which by open-loop insulin supply schemes.

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